Diagnosis
Since there is no specific test or marker for PD, diagnosis is by a physician and depends on the presence of at least two of the three major signs: tremor at rest, rigidity, and bradykinesia, as well as the absence of a secondary cause, such as antipsychotic medications or multiple small strokes in the regions of the brain controlling movement. Patients tend to be most aware of tremor and bradykinesia, and less so of rigidity.
To diagnose PD, the physician will perform a standard neurological examination, involving various simple tests of reactions, reflexes, and movements.
- Bradykinesia is tested by determining how quickly the person can tap the finger and thumb together, or tap the foot up and down.
- Tremor is determined by simple inspection.
- The physician assesses rigidity by moving the neck, upper limbs, and lower limbs while the patient relaxes, feeling for resistance to movement.
- Postural instability is tested with the "pull test," in which the examiner stands behind the patient and asks the patient to maintain their balance when pulled backwards. The examiner pulls back briskly to assess the patient's ability to recover, being careful to prevent the patient from falling.
Symptoms
The cardinal motor symptoms are slowed movements (called bradykinesia), resting tremor (shaking in an arm or leg when it is not being moved), muscle rigidity (stiffness), and postural instability. Other symptoms are listed in the Box below. Symptoms typically begin on one side of the body (unilateral) and progress to include both sides.
Symptoms of Parkinson's Disease
(Not all people with PD develop all these symptoms.)
-
* Motor Symptoms
- Tremor
- Bradykinesia
- Rigidity and freezing in place
- Stooped, shuffling gait
- Decreased arm swing when walking
- Difficulty arising from a chair
- Micrographia (small handwriting)
- Lack of facial expression
- Slowed activities of daily living
- Postural instability
- Difficulty turning in bed
-
* Nonmotor Symptoms
- Diminished sense of smell
- Low voice volume
- Painful foot cramps
- Sleep disturbance
- Depression
- Constipation
- Drooling
- Increased sweating
- Urinary frequency/urgency
- Male erectile dysfunction
